Chemistry of ROS-mediated oxidation to the guanine base in DNA and its biological consequences
Author:
Affiliation:
1. Department of Chemistry, University of Utah, Salt Lake City, UT, USA
Funder
National Cancer Institute
National Institute of General Medical Sciences
Publisher
Informa UK Limited
Subject
Radiology, Nuclear Medicine and imaging,Radiological and Ultrasound Technology
Link
https://www.tandfonline.com/doi/pdf/10.1080/09553002.2021.2003464
Reference77 articles.
1. Crystal Structure of a Replicative DNA Polymerase Bound to the Oxidized Guanine Lesion Guanidinohydantoin ,
2. Guanine Oxidation Product 5-Carboxamido-5-formamido-2-iminohydantoin Induces Mutations When Bypassed by DNA Polymerases and Is a Substrate for Base Excision Repair
3. 5-Carboxamido-5-formamido-2-iminohydantoin, in Addition to 8-oxo-7,8-Dihydroguanine, Is the Major Product of the Iron-Fenton or X-ray Radiation-Induced Oxidation of Guanine under Aerobic Reducing Conditions in Nucleoside and DNA Contexts
4. Genome-wide mapping of 8-oxo-7,8-dihydro-2′-deoxyguanosine reveals accumulation of oxidatively-generated damage at DNA replication origins within transcribed long genes of mammalian cells
5. Isolation and Characterization of the Radiation-Induced Degradation Products of 2′-Deoxyguanosine in Oxygen-Free Aqueous Solutions
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