Romiplostim (Nplate®) as an effective radiation countermeasure to improve survival and platelet recovery in mice
Author:
Affiliation:
1. SRI Biosciences, SRI International, Menlo Park, CA, USA;
2. Amgen, Thousand Oaks, CA, USA
Funder
National Institue of Allergy and Infectious Diseases, National Institues of Health, Dept. of Health and Human Services
Publisher
Informa UK Limited
Subject
Radiology, Nuclear Medicine and imaging,Radiological and Ultrasound Technology
Link
https://tandfonline.com/doi/pdf/10.1080/09553002.2019.1605465
Reference31 articles.
1. Acute Gastrointestinal Syndrome in High-Dose Irradiated Mice
2. AMG531 stimulates megakaryopoiesis in vitro by binding to Mpl
3. Survival Efficacy of the PEGylated G-CSFs Maxy-G34 and Neulasta in a Mouse Model of Lethal H-ARS, and Residual Bone Marrow Damage in Treated Survivors
4. A Single Intravenous Dose of Murine Megakaryocyte Growth and Development Factor Potently Stimulates Platelet Production, Challenging the Necessity for Daily Administration
5. Pegfilgrastim Administered in an Abbreviated Schedule, Significantly Improved Neutrophil Recovery after High-Dose Radiation-Induced Myelosuppression in Rhesus Macaques
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