Preclinical target validation for non-addictive therapeutics development for pain

Author:

Hargreaves Richard1,Akinsanya Karen2,Ajit Seena K.3ORCID,Dhruv Neel T.4ORCID,Driscoll Jamie5,Farina Peter6,Gavva Narender7,Gill Marie4,Houghton Andrea8,Iyengar Smriti4,Jones Carrie9,Kavelaars Annemieke10,Kaykas Ajamete11,Koroshetz Walter J.4,Laeng Pascal4,Laird Jennifer M.12,Lo Donald C.13,Luthman Johan14,Munro Gordon15ORCID,Oshinsky Michael L.4,Sittampalam G. Sitta13,Woller Sarah A.4,Tamiz Amir P.4

Affiliation:

1. Bristol Myers Squibb, New York, New York, United States

2. Schrödinger LLC, New York, New York, United States

3. Department of Pharmacology, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States

4. National Institute of Neurological Disorders and Stroke, Bethesda, Maryland, United States

5. National Institute of Mental Health, Bethesda, Maryland, United States

6. Canaan Partners, Westport, Connecticut, United States

7. Drug Discovery Sciences, Takeda Pharmaceuticals, San Diego, California, United States

8. Merck & Co Inc, Kenilworth, New Jersey, United States

9. Department of Pharmacology, Vanderbilt University, Nashville, Tennessee, United States

10. The University of Texas MD Anderson Cancer Center, Houston, Texas, United States

11. Insitro, San Francisco, California, United States

12. Eli Lilly and Company, Windlesham, United Kingdom of Great Britain and Northern Ireland

13. National Center for Advancing Translational Sciences, Bethesda, Maryland, United States

14. Lundbeck, Valby, Denmark

15. Hoba Therapeutics, Copenhagen, Denmark

Publisher

Informa UK Limited

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Medicine

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