The use of LP533401 as a therapeutic option for renal osteodystrophy affects, renal calcium handling, vitamin D metabolism, and bone health in uremic rats
Author:
Affiliation:
1. Department of Pharmacodynamics, Medical University of Bialystok, Bialystok, Poland
2. Department of Monitored Pharmacotherapy, Medical University of Bialystok, Bialystok, Poland
Funder
National Science Centre
Uniwersytet Medyczny w Bialymstoku
Publisher
Informa UK Limited
Subject
Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/14728222.2019.1586883
Reference32 articles.
1. Regulation of serum phosphate
2. Calcium Metabolism in Health and Disease
3. The Combination of Vitamin D Deficiency and Mild to Moderate Chronic Kidney Disease Is Associated With Low Bone Mineral Density and Deteriorated Femoral Microarchitecture: Results From the KNHANES 2008–2011
4. ORIGINAL ARTICLE: Association between 25-hydroxyvitamin D, somatic muscle weakness and falls risk in end-stage renal failure
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3. Modulation of the Paracrine Kynurenic System in Bone as a New Regulator of Osteoblastogenesis and Bone Mineral Status in an Animal Model of Chronic Kidney Disease Treated with LP533401;International Journal of Molecular Sciences;2020-08-19
4. Inhibition of peripheral serotonin synthesis by LP533401 and disturbances in calciotropic hormones attenuated excessive osteoblastogenesis with simultaneous improvement of bone mineral status in 5/6 nephrectomized rats;Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease;2019-11
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