Unraveling therapeutic targets in acute myeloid leukemia through multiplexed genome editing CRISPR screening
Author:
Affiliation:
1. Coriell Institute for Medical Research, Camden, NJ, USA
2. Center for Metabolic Disease Research, Temple University Lewis Katz School of Medicine, Philadelphia, PA, USA
3. Cooper Medical School of Rowan University, Camden, NJ, USA
Funder
NCI
the Coriell Institute for Medical Research awarded to J. Huang
Publisher
Informa UK Limited
Subject
Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/14728222.2023.2293751
Reference15 articles.
1. Multiplex Genome Engineering Using CRISPR/Cas Systems
2. RNA-Guided Human Genome Engineering via Cas9
3. Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
4. Improved vectors and genome-wide libraries for CRISPR screening
5. A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia
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