Interdependence of Baseline Correction Method and Covariance Structure for Crossover TQT Studies

Author:

Li Wenqing1,Maes Andrea2,Quinlan Michelle1,Anand Suraj1

Affiliation:

1. a Biometrics and Data Management , Novartis Pharmaceuticals , Florham Park , New Jersey , USA

2. b Watson Pharmaceuticals, Inc. , Parsippany , New Jersey , USA

Publisher

Informa UK Limited

Subject

Pharmacology (medical),Pharmacology,Statistics and Probability

Cited by 5 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Concentration-QTc analysis with two or more correlated baselines;Journal of Pharmacokinetics and Pharmacodynamics;2021-05-12

2. Novel concentration‐QTc models for early clinical studies with parallel placebo controls: A simulation study;Pharmaceutical Statistics;2020-12-08

3. Checking identifiability of covariance parameters in linear mixed effects models;Journal of Applied Statistics;2016-10-04

4. Identifiability of covariance parameters in linear mixed effects models;Linear Algebra and its Applications;2016-10

5. Cardiovascular toxicity, especially QT/QTc prolongation;Statistical Methods for Evaluating Safety in Medical Product Development;2014-12-12

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