Design optimization for dose-finding trials: a review
Author:
Affiliation:
1. Research and Development, Sanofi, Chilly-Mazarin, France
2. IMAG, Univ Montpellier, CNRS, Montpellier, France
3. Lemon, INRIA, Montpellier, France
Publisher
Informa UK Limited
Subject
Pharmacology (medical),Pharmacology,Statistics and Probability
Link
https://www.tandfonline.com/doi/pdf/10.1080/10543406.2020.1730874
Reference29 articles.
1. Optimizing Drug Development Programs: Type 2 Diabetes Case Study
2. Impact of Dose Selection Strategies Used in Phase II on the Probability of Success in Phase III
3. Évaluation des approches basées sur le test de Dunnett et MCP-Mod dans des essais de détermination de dose en deux étapes
4. Utility-Based Dose-Finding in Practice: Some Empirical Contributions and Recommendations
5. Design evaluation and optimisation in multiple response nonlinear mixed effect models: PFIM 3.0
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