Combined QSAR-based virtual screening and fluorescence binding assay to identify natural product mediators of Interferon Regulatory Factor 7 (IRF-7) in pulmonary infection
Author:
Affiliation:
1. Centre of Infectious Diseases, West China Hospital, Sichuan University, Chengdu, China
Publisher
Informa UK Limited
Subject
Drug Discovery,Molecular Medicine,General Medicine,Bioengineering
Link
https://www.tandfonline.com/doi/pdf/10.1080/1062936X.2016.1243576
Reference32 articles.
1. Monocyte Differentiation to Macrophage Requires Interferon Regulatory Factor 7
2. IRF7: activation, regulation, modification and function
3. Lung epithelium as a sentinel and effector system in pneumonia – molecular mechanisms of pathogen recognition and signal transduction
4. Acute and Chronic Airway Responses to Viral Infection: Implications for Asthma and Chronic Obstructive Pulmonary Disease
5. Small-Molecule Interferon Inducers. Toward the Comprehension of the Molecular Determinants through Ligand-Based Approaches
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