Probing molecular mechanism of inhibitor bindings to bromodomain-containing protein 4 based on molecular dynamics simulations and principal component analysis-Reference-Cited by-同舟云学术

Probing molecular mechanism of inhibitor bindings to bromodomain-containing protein 4 based on molecular dynamics simulations and principal component analysis

Published:2020-06-17 Issue:7 Volume:31 Page:547-570
ISSN:1062-936X
Container-title:SAR and QSAR in Environmental Research
language:en
Short-container-title:SAR and QSAR in Environmental Research

Author:

Wu S.L.¹^ORCID,Wang L.F.¹^ORCID,Sun H.B.¹,Wang W.¹,Yu Y.X.¹

Affiliation:

1. School of Science, Shandong Jiaotong University, Jinan, China

Funder

National Natural Science Foundation of China

Shandong Provincial Natural Science Foundation of China

Science Foundation of Shandong Jiaotong University

Publisher

Informa UK Limited

Subject

Drug Discovery,Molecular Medicine,General Medicine,Bioengineering

Link

https://www.tandfonline.com/doi/pdf/10.1080/1062936X.2020.1777584

Reference100 articles.

1. Chromatin Modifications and Their Function

2. Reading signals on the nucleosome with a new nomenclature for modified histones

3. Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders

4. brahma: A regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2SWI2

5. The bromodomain: a conserved sequence found in human,Drosophilaand yeast proteins

Cited by 15 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Unveiling Allosteric Regulation and Binding Mechanism of BRD9 through Molecular Dynamics Simulations and Markov Modeling;Molecules;2024-07-25

2. Selectivity Mechanism of Pyrrolopyridone Analogues Targeting Bromodomain 2 of Bromodomain-Containing Protein 4 from Molecular Dynamics Simulations;ACS Omega;2023-09-06

3. Unveiling the Inhibitory Potentials of Peptidomimetic Azanitriles and Pyridyl Esters towards SARS-CoV-2 Main Protease: A Molecular Modelling Investigation;Molecules;2023-03-14

4. Structural Investigations and Binding Mechanisms of Oseltamivir Drug Resistance Conferred by the E119V Mutation in Influenza H7N9 Virus;Molecules;2022-07-08

5. Computational studies with flavonoids and terpenoids as BRPF1 inhibitors: in silico biological activity prediction, molecular docking, molecular dynamics simulations, MM/PBSA calculations;SAR and QSAR in Environmental Research;2022-07-03