In Ataxia-Telangiectasia, Oral Betamethasone Administration Ameliorates Lymphocytes Functionality through Modulation of the IL-7/IL-7Rα Axis Paralleling the Neurological Behavior: A Comparative Report of Two Cases-Reference-Cited by-同舟云学术

In Ataxia-Telangiectasia, Oral Betamethasone Administration Ameliorates Lymphocytes Functionality through Modulation of the IL-7/IL-7Rα Axis Paralleling the Neurological Behavior: A Comparative Report of Two Cases

Published:2020-05-13 Issue:2-3 Volume:50 Page:295-303
ISSN:0882-0139
Container-title:Immunological Investigations
language:en
Short-container-title:Immunological Investigations

Author:

Prencipe Rosaria¹,Cirillo Emilia¹,Giardino Giuliana¹,Gallo Vera¹,Menotta Michele²,Magnani Mauro²,Barone Maria Vittoria¹,Palamaro Loredana¹,Scalia Giulia³,Del Vecchio Luigi³,Pignata Claudio¹

Affiliation:

1. Department of Translational Medical Sciences-Section of Pediatrics, Federico II University, Naples, Italy

2. Department of Biomolecular Sciences, University of Urbino “Carlo Bo”, Urbino, Italy

3. Department of Biochemistry and Medical Biotechnology–CEINGE, Federico II University, Naples, Italy

Funder

Ministero della Salute

Publisher

Informa UK Limited

Subject

General Medicine,Immunology

Link

https://www.tandfonline.com/doi/pdf/10.1080/08820139.2020.1761379

Reference18 articles.

1. Effect of Class Switch Recombination Defect on the Phenotype of Ataxia-Telangiectasia Patients

2. Cutaneous Granulomatosis and Class Switching Defect as a Presenting Sign in Ataxia-Telangiectasia: First Case from the National Iranian Registry and Review of the Literature

3. Recycled IL-7 Can Be Delivered to Neighboring T Cells

4. Steroid-induced improvement of neurological signs in ataxia-telangiectasia patients

5. Efficacy of very-low-dose betamethasone on neurological symptoms in ataxia-telangiectasia

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1. MicroRNA dysregulation in ataxia telangiectasia;Frontiers in Immunology;2024-08-19

2. Dexamethasone induces p21^cip1/waf1 expression via FoxO3a independently of the Lamin A/C‐HDAC2 interaction in Ataxia Telangiectasia;FEBS Open Bio;2023-07-03

3. Progressive Depletion of B and T Lymphocytes in Patients with Ataxia Telangiectasia: Results of the Italian Primary Immunodeficiency Network;Journal of Clinical Immunology;2022-03-08

4. Transcriptomic profile of ataxia telangiectasia cells treated for 30 days with a low dose of dexamethasone;All Life;2021-01-01