PCSK9 Suppresses M2-Like Tumor-Associated Macrophage Polarization by Regulating the Secretion of OX40L from Hepatocellular Carcinoma Cells-Reference-Cited by-同舟云学术

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PCSK9 Suppresses M2-Like Tumor-Associated Macrophage Polarization by Regulating the Secretion of OX40L from Hepatocellular Carcinoma Cells

Published:2022-01-25 Issue:6 Volume:51 Page:1678-1693
ISSN:0882-0139
Container-title:Immunological Investigations
language:en
Short-container-title:Immunological Investigations

Author:

Hu Jing¹,Zhang Meixia²,Gui Ling²,Wan Qinsi²,Zhong Jiawei²,Bai Liangliang²,He Mingyan²³

Affiliation:

1. Department of Cardiology, Jiangxi Provincial People’s Hospital Affiliated to Nanchang University, Nanchang, Jiangxi, China

2. Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China

3. Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China

Funder

Education Department of Jiangxi Province

Jiangxi Provincial Department of Science and Technology

National Natural Science Foundation of China

Publisher

Informa UK Limited

Subject

General Medicine,Immunology

Link

https://www.tandfonline.com/doi/pdf/10.1080/08820139.2022.2027439

Reference46 articles.

1. PCSK9 inhibition, atherosclerotic cardiovascular disease, and health economics: Challenges at the crossroads

2. Hepatocellular carcinoma-associated hypercholesterolemia: involvement of proprotein-convertase-subtilisin-kexin type-9 (PCSK9)

3. Decreased PCSK9 expression in human hepatocellular carcinoma

4. STAT3/NF‐κB signalling disruption in M2 tumour‐associated macrophages is a major target of PLGA nanocarriers/PD‐L1 antibody immunomodulatory therapy in breast cancer

5. Hepatocellular Carcinoma: Review of Epidemiology, Screening, Imaging Diagnosis, Response Assessment, and Treatment

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1. Biological impact and therapeutic implication of tumor-associated macrophages in hepatocellular carcinoma;Cell Death & Disease;2024-07-12

2. Targeting proprotein convertase subtilisin/kexin type 9 (PCSK9): from bench to bedside;Signal Transduction and Targeted Therapy;2024-01-08

3. Association between serum PCSK9 and coronary heart disease in patients with type 2 diabetes mellitus;Diabetology & Metabolic Syndrome;2023-12-20

4. The role of tumor‐associated macrophages in hepatocellular carcinoma progression: A narrative review;Cancer Medicine;2023-12

5. IL8 derived from macrophages inhibits CD8+ T-cell function by downregulating TIM3 expression through IL8-CXCR2 axis in patients with advanced colorectal cancer;International Immunopharmacology;2023-08

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