Antioxidative properties of ginsenoside Ro against UV-B-induced oxidative stress in human dermal fibroblasts-Reference-Cited by-同舟云学术

Antioxidative properties of ginsenoside Ro against UV-B-induced oxidative stress in human dermal fibroblasts

Published:2015-12-02 Issue:12 Volume:79 Page:2018-2021
ISSN:0916-8451
Container-title:Bioscience, Biotechnology, and Biochemistry
language:en
Short-container-title:

Author:

Kang Hyun Ji¹,Oh Yuri¹,Lee Sihyeong²,Ryu In Wang¹,Kim Kyunghoon¹,Lim Chang-Jin²

Affiliation:

1. Department of Biological Sciences, Kangwon National University, Chuncheon, Republic of Korea

2. Department of Biochemistry, Kangwon National University, Chuncheon, Republic of Korea

Abstract

Abstract Ginsenoside Ro (Ro), an oleanolic acid-type ginsenoside, exhibited suppressive activities on reactive oxygen species (ROS) and matrix metalloproteinase-2 (MMP-2) elevation in UV-B-irradiated fibroblasts. Ro could overcome the reduction of the total glutathione (GSH) contents in UV-B-irradiated fibroblasts. Ro could not interfere with cell viabilities in UV-B-irradiated fibroblasts. Collectively, Ro possesses a potential skin anti-photoaging property against UV-B radiation in fibroblasts.

Funder

Korea Healthcare Technology R & D Project, Ministry of Health & Welfare, Republic of Korea

Publisher

Oxford University Press (OUP)

Subject

Organic Chemistry,Molecular Biology,Applied Microbiology and Biotechnology,General Medicine,Biochemistry,Analytical Chemistry,Biotechnology

Link

http://academic.oup.com/bbb/article-pdf/79/12/2018/36820585/bbb2018.pdf

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