Short-step syntheses of naturally occurring polyoxygenated aromatics based on site-selective transformation-Reference-Cited by-同舟云学术

Short-step syntheses of naturally occurring polyoxygenated aromatics based on site-selective transformation

Published:2017-07-03 Issue:7 Volume:81 Page:1279-1284
ISSN:0916-8451
Container-title:Bioscience, Biotechnology, and Biochemistry
language:en
Short-container-title:

Author:

Yamashita Yasunobu¹,Biard Alan¹²,Hanaya Kengo¹,Shoji Mitsuru¹,Sugai Takeshi¹

Affiliation:

1. Department of Pharmaceutical Sciences, Faculty of Pharmacy, Keio University, Tokyo, Japan

2. Department of Chemistry, Graduate School of SIGMA Clermont, Aubiere Cedex, France

Abstract

Abstract Wogonin and astringin were synthesized from inexpensive chrysin and piceid in short steps. The key feature of these syntheses is site-selective transformation. The target molecules were obtained in 27 and 62% yields from the starting materials, respectively.

Funder

Platform for Drug Discovery, Informatics, and Structural Life Science

grant-aid for scientific research

Publisher

Oxford University Press (OUP)

Subject

Organic Chemistry,Molecular Biology,Applied Microbiology and Biotechnology,General Medicine,Biochemistry,Analytical Chemistry,Biotechnology

Link

http://academic.oup.com/bbb/article-pdf/81/7/1279/36823849/bbb1279.pdf

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