Desmodianone H and uncinanone B, potential tyrosinase inhibitors obtained from Lespedeza maximowiczii by using bioactivity-guided isolation-Reference-Cited by-同舟云学术

Desmodianone H and uncinanone B, potential tyrosinase inhibitors obtained from Lespedeza maximowiczii by using bioactivity-guided isolation

Published:2014-06-03 Issue:6 Volume:78 Page:943-945
ISSN:0916-8451
Container-title:Bioscience, Biotechnology, and Biochemistry
language:en
Short-container-title:

Author:

Heo Do Yeon¹,Kim Young Mi¹,Lee Joongku²,Park Sang-Hong²,Kim Jinki²,Park Hye Min¹,Lee Choong Hwan¹

Affiliation:

1. Department of Bioscience and Biotechnology, Konkuk University, Seoul, Republic of Korea

2. International Biological Material Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea

Abstract

Abstract A new bioactive compound, namely desmodianone H (1), and another known compound uncinanone B (2) were first isolated using bioactivity-guided isolation from the leaves of Lespedeza maximowiczii and structures were elucidated by comprehensive analysis of their nuclear magnetic resonance and mass spectrometry data. Compounds 1 and 2 exhibited strong inhibitory effects on mushroom tyrosinase activity.

Publisher

Oxford University Press (OUP)

Subject

Organic Chemistry,Molecular Biology,Applied Microbiology and Biotechnology,General Medicine,Biochemistry,Analytical Chemistry,Biotechnology

Link

http://academic.oup.com/bbb/article-pdf/78/6/943/36798757/bbb0943.pdf

Reference17 articles.

1. Phylogenetic analysis of eastern Asian and eastern North American disjunct Lespedeza (Fabaceae) inferred from nuclear ribosomal ITS and plastid region sequences

2. Hybridization between the threatened plant, Lespedeza leptostachya Englem. and its co-occurring congener Lespedeza capitata Michx.: morphological and molecular evidence

3. Studies on the Constituents of Lespedeza homoloba NAKAI. I. The Structure of Lespedeol A

4. Studies on the Constituents of Lespedeza homoloba NAKAI. III. The Structures of Lespein and Lespedezin

5. Antioxidants from Lespedeza homoloba (II)

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