Affiliation:
1. Nagaragawa Research Center, Api Co. Ltd., Gifu, Japan
Abstract
Abstract
A novel 2-phenoxychromone (1) and five known flavones (2-6) were isolated from northeastern Brazilian propolis in the state of Bahia. The chemical structures of these six compounds were determined by spectroscopic investigations and single-crystal X-ray analysis. The isolated compounds showed growth-inhibitory activities, in varying degrees, against human tumor cell lines. This is the first report on the discovery of a novel 2-phenoxychromone from propolis.
Publisher
Oxford University Press (OUP)
Subject
Organic Chemistry,Molecular Biology,Applied Microbiology and Biotechnology,General Medicine,Biochemistry,Analytical Chemistry,Biotechnology
Reference32 articles.
1. Isolation and identification of antimicrobial compounds in Brazilian Propolis;Aga;Biosci Biotechnol Biochem,1994
2. Antibacterial, antifungal and antiviral activity of propolis of different geographic origin;Kujumgieva;J Ethnopharmacol,1999
3. Effect of seasonality on chemical composition and antibacterial and anticandida activities of Argentine propolis. Design of a topical formulation;Isla;Nat Prod Commun,2012
4. 3,4-Dicaffeoylquinic acid, a major constituent of Brazilian Propolis, increases TRAIL expression and extends the lifetimes of mice infected with the influenza a virus;Takemura;Evid Based Complement Alternat Med,2012
5. Anti-inflammatory effects of a bioavailable compound, Artepillin C Brazilian propolis;Paulino;Eur J Pharmacol,2008
Cited by
12 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献