Polyphenols from flowers of Magnolia coco and their anti-glycation effects

Author:

Kato Nana1,Kawabe Satoko1,Ganeko Natsuki1,Yoshimura Morio2,Amakura Yoshiaki2,Ito Hideyuki1

Affiliation:

1. Faculty of Health and Welfare Science, Department of Nutritional Science, Okayama Prefectural University, Okayama, Japan

2. Department of Pharmacognosy, College of Pharmaceutical Sciences, Matsuyama University, Matsuyama, Japan

Abstract

Abstract We investigated the inhibitory effects of several plant extracts on advanced glycation end-products (AGEs) formation. Among tested samples, the flower extract of Magnolia coco showed significant inhibition of AGE formation. We isolated and characterized procyanidin oligomer and four other compounds from the flowers, and evaluated their inhibitory effects on AGE formation and the AGE-derived crosslink-cleaving activity of the isolated compounds.

Publisher

Oxford University Press (OUP)

Subject

Organic Chemistry,Molecular Biology,Applied Microbiology and Biotechnology,General Medicine,Biochemistry,Analytical Chemistry,Biotechnology

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