Barrier crossing in dihydrofolate reductase does not involve a rate-promoting vibration
Author:
Publisher
Informa UK Limited
Subject
Physical and Theoretical Chemistry,Condensed Matter Physics,Molecular Biology,Biophysics
Link
http://www.tandfonline.com/doi/pdf/10.1080/00268976.2012.655337
Reference23 articles.
1. Intrinsic motions along an enzymatic reaction trajectory
2. Enzymatic transition states and dynamic motion in barrier crossing
3. Loop and Subdomain Movements in the Mechanism of Escherichia coli Dihydrofolate Reductase: Crystallographic Evidence,
4. Coupling Interactions of Distal Residues Enhance Dihydrofolate Reductase Catalysis: Mutational Effects on Hydride Transfer Rates
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