1. For a review of this topic, see A.W. Czarnik, inMechanistic Principles of Enzyme ActivityActivity, edited by J.F. Liebman and A. Greenberg (VCH, New York, 1988); T.C. Bruice and S.J. Benkovic,Bioorganic Mechanisms, Vols. I and II (Benjamin, Reading, MA, 1966); W.P. Jencks,Catalysis in Chemistry and Enzymology(McGraw, New York, 1969); M.L. Bender,Mechanism of Homogeneous Catalysis from Protons to Proteins(Wiley–Interscience, New York, 1971); D.L. Nelson and M.M. Cox,Lehninger Principles of Biochemistry(Worth, New York, 2003); A. Fersht,Structure and Mechanism in Protein Science: A guide to Enzyme Catalysis and Protein Folding(W. H. Freeman, New York, 1999); R. Pascal, Eur. J. Org. Chem. 1813 (2003); R. Pascal, Bioorg. Chem.31, 485 (2003); G.F. Sweigers,Mechanical Catalysis(Wiley, Hoboken, NJ, 2008); C. Walsh,Enzymatic Reaction Mechanism(Freeman, San Francisco, 1979); M.I. Page, inEnzyme Mechanisms, edited by M.I. Page and A. Williams (Royal Society of Chemistry, London, 1987), p. 1; R.B. Silverman,The Organic Chemistry of Enzyme-Catalyzed Reactions(Academic Press, San Diego, 2002); R. Pascal, Eur. J. Org. Chem. 1813 (2003); D.A. Kraut, K.S. Carroll and D. Herschlag, Annu. Rev. Biochem.72, 517 (2003); A. Radzicka and R. Wolfenden, J. Am. Chem. Soc.118, 6105 (1996); M.J. Snider and R. Wolfenden, J. Am. Chem. Soc.122, 11507 (2000); M.I. Page and W.P. Jencks, Proc. Natn. Acad. Sci. USA68, 1678 (1971); M.I. Page and W.P. Jencks, Gazz. Chim. Ital.117, 455 (1987); M.I. Page, Chem. Soc. Rev.2, 295 (1973); M.I. Page, Angew. Chem. Int. Ed. Engl.16, 449 (1977).
2. Remote enzyme-coupled amine release
3. Ground State and Transition State Contributions to the Rates of Intramolecular and Enzymatic Reactions
4. Theoretical Aspects of Orbital Steering
5. Concurrent general-acid and general-base catalysis of esterification