Use of NPE-Protecting Groups for the Preparation of Oligonucleotides Without Using Nucleophiles During the Final Deprotection

Author:

Avino A. M.,Eritja R.

Publisher

Informa UK Limited

Subject

Genetics,Biochemistry

Reference24 articles.

1. Eckstein, F., ed. 1991. “Oligonucleotides and analogues. A practical approach”. Oxford: Oxford Univerity Press.

2. The Functionalization of Oligonucleotides Via Phosphoramidite Derivatives

3. The final deprotection step in oligonucleotide synthesis is reduced to a mild and rapid ammonia treatment by using labile base-protecting groups

4. Sinha, N and Casale, R. 1992. “Tenth International Round Table. Nucleosides and Nucleotides and their Biological Applications”. Park City, Utah, USA

5. Fast oligonucleotide deprotection phosphoramidite chemistry for DNA synthesis

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5. Protection for the Phosphate Group;Greene's Protective Groups in Organic Synthesis;2014-08-11

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