Masitinib as an add-on therapy to riluzole in patients with amyotrophic lateral sclerosis: a randomized clinical trial

Author:

Mora Jesus S.1,Genge Angela2,Chio Adriano3ORCID,Estol Conrado J.4,Chaverri Delia5,Hernández Maria5,Marín Saúl5,Mascias Javier5,Rodriguez Gabriel E.6,Povedano Monica7,Paipa Andrés7,Dominguez Raul7,Gamez Josep8ORCID,Salvado Maria8,Lunetta Christian9,Ballario Carlos10,Riva Nilo11,Mandrioli Jessica12,Moussy Alain13,Kinet Jean-Pierre1314,Auclair Christian1315,Dubreuil Patrice1316,Arnold Vincent13,Mansfield Colin D.13,Hermine Olivier1317,

Affiliation:

1. ALS Unit, Hospital San Rafael, Madrid, Spain;

2. Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montreal, Canada;

3. Department of Neuroscience, University of Turin, Turin, Italy;

4. Neurological Center for Treatment and Rehabilitation, Buenos Aires, Argentina;

5. Department of Neurology, ALS Unit, Hospital Carlos III, Madrid, Spain;

6. Neurology Department, Neuron Motor Disease Clinic, Hospital JM Ramos, Buenos Aires, Argentina;

7. Neurology Department, Bellvitge Hospital-IDIBELL, Barcelona, Spain;

8. Neurology Department, Vall d’Hebron University Hospital, Vall d’Hebron Research Institute, Autonomous University of Barcelona, Barcelona, Spain;

9. NEMO Clinical Centre, Serena Onlus Foundation, Milan, Italy;

10. Neurorosario, Rosario, Argentina;

11. Department of Neurology-INSPE, San Raffaele Scientific Institute, Milan, Italy;

12. Department of Neurosciences, St. Agostino-Estense Hospital, Azienda Ospedaliero Universitaria di Modena, Modena, Italy;

13. AB Science, Paris, France;

14. Department of Pathology, Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, MA, USA;

15. Department of Biology, Université Paris Sud Université Paris-Saclay CNRS UMR 8113, Ecole Normale Supérieure de Cachan, Cachan, France;

16. INSERM, CNRS, Institut Paoli-Calmettes, CRCM, Centre de Référence des Mastocytoses, Equipe Labelisée Ligue Nationale Contre le Cancer, Aix-Marseille University, Marseille, France; and

17. Imagine Institute, INSERM UMR 1163 and CNRS ERL 8254, Laboratory of Cellular and Molecular Mechanisms of Hemathological Disorders and Therapeutic Implication, Hôpital Necker, Paris, France

Funder

AB Science

Publisher

Informa UK Limited

Subject

Clinical Neurology,Neurology

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