High rate of improvement in serum matrix metalloproteinase-3 levels at 4 weeks predicts remission at 52 weeks in RA patients treated with adalimumab

Author:

Hattori Yosuke1,Kojima Toshihisa2,Kaneko Atsushi1,Kida Daihei1,Hirano Yuji3,Fujibayashi Takayoshi4,Yabe Yuichiro5,Oguchi Takeshi6,Kanayama Yasuhide7,Miyake Hiroyuki8,Kato Takefumi9,Takagi Hideki10,Hayashi Masatoshi11,Ito Takayasu12,Shioura Tomone13,Takahashi Nobunori2,Ishikawa Hisato14,Funahashi Koji15,Ishiguro Naoki2

Affiliation:

1. Department of Orthopaedic Surgery and Rheumatology, National Hospital Organization Nagoya Medical Center, Nagoya, Japan;

2. Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan;

3. Department of Rheumatology, Toyohashi Municipal Hospital, Toyohashi, Japan;

4. Department of Orthopaedic Surgery, Konan Kosei Hospital, Konan, Japan;

5. Department of Rheumatology, Japan Community Healthcare Organization Tokyo Shinjuku Medical Center, Tokyo, Japan;

6. Department of Orthopaedic Surgery, Anjo Kosei Hospital, Anjo, Japan;

7. Department of Orthopedic Surgery and Rheumatology, Toyota Kosei Hospital, Toyota, Japan;

8. Department of Orthopaedic Surgery, Ichinomiya Municipal Hospital, Ichinomiya, Japan;

9. Kato Clinic, Okazaki, Japan;

10. Department of Orthopaedic Surgery, Nagoya Central Hospital, Nagoya, Japan;

11. Department of Rheumatology, Nagano Red Cross Hospital, Nagano, Japan;

12. Ito Seikeigeka, Nagoya, Japan;

13. Shizuoka Kosei Hospital, Shizuoka, Japan;

14. Department of Orthopaedic Surgery, Japanese Red Cross Nagoya Daiichi Hospital, Nagoya, Japan;

15. Department of Orthopaedic Surgery, Kariya Toyota General Hospital, Kariya, Japan

Funder

Chugai Pharmaceutical

Pfizer

Abbvie

UCB

Bristol-Myers Squibb

Janssen Pharmaceuticals

Mitsubishi Tanabe Pharma

Takeda Pharmaceutical Compan

Eisai

AbbVie

Astellas Pharma

Taisho Toyama Pharmaceutical Company

Daiichi Sankyo Company

Takeda Pharmaceutical

AYUMI Pharmaceutical

Mitsubishi Tanabe Pharmaceutical

Mitsubishi Tanabe Pharma Corporation

Janssen Pharmaceutical

Daiichi Sankyo

Hisamitsu Pharmaceutical

Otsuka Pharmaceutical

Kaken Pharmaceutical

Abbott Japan

Publisher

Oxford University Press (OUP)

Subject

Rheumatology

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