A phase 2a, randomized, double-blind, placebo-controlled trial of the efficacy and safety of the oral gonadotropin-releasing hormone antagonist, ASP1707, in postmenopausal female patients with rheumatoid arthritis taking methotrexate-Reference-Cited by-同舟云学术

A phase 2a, randomized, double-blind, placebo-controlled trial of the efficacy and safety of the oral gonadotropin-releasing hormone antagonist, ASP1707, in postmenopausal female patients with rheumatoid arthritis taking methotrexate

Published:2020-03-03 Issue:1 Volume:31 Page:53-60
ISSN:1439-7595
Container-title:Modern Rheumatology
language:en
Short-container-title:Modern Rheumatology

Author:

Takeuchi Tsutomu¹,Tanaka Yoshiya²,Higashitani Chieri³,Iwai Megumi⁴,Komatsu Kanji⁵,Akazawa Rio⁶,Lademacher Christopher⁷

Affiliation:

1. Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan

2. The First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan

3. Clinical Development, Astellas Pharma, Inc., Tokyo, Japan

4. Clinical Pharmacology and Exploratory Development, Astellas Pharma, Inc., Tokyo, Japan

5. Clinical Pharmacology, Astellas Pharma, Inc., Tokyo, Japan

6. Data Science, Astellas Pharma, Inc., Tokyo, Japan

7. Medical Science, Astellas Pharma, Inc., Northbrook, IL, USA

Funder

Astellas Pharma Inc

Publisher

Oxford University Press (OUP)

Subject

Rheumatology

Link

https://www.tandfonline.com/doi/pdf/10.1080/14397595.2020.1733214

Reference22 articles.

1. Rheumatoid arthritis: pathological mechanisms and modern pharmacologic therapies

2. The global burden of rheumatoid arthritis: estimates from the Global Burden of Disease 2010 study

3. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update

4. Novel drug delivery systems for NSAIDs in management of rheumatoid arthritis: An overview

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