Efficacy and safety of canakinumab in systemic juvenile idiopathic arthritis: 48-week results from an open-label phase III study in Japanese patients

Author:

Nishimura Kenichi1,Hara Ryoki1,Umebayashi Hiroaki2,Takei Syuji3,Iwata Naomi4,Imagawa Tomoyuki5,Shimizu Masaki6,Tomiita Minako7,Seko Noriko8,Kitawaki Tetsuji8,Yokota Shumpei9

Affiliation:

1. Department of Pediatrics, Yokohama City University Graduate School of Medicine, Yokohama, Japan

2. Department of Rheumatology and Infectious Disease, Miyagi Children’s Hospital, Sendai, Japan

3. School of Medical and Dental Sciences Pediatrics, Kagoshima University Graduate, Kagoshima, Japan

4. Department of Infection and Immunology, Aichi Children’s Health and Medical Center, Obu, Japan

5. Department of Infection and Immunology, Kanagawa Children’s Medical Center, Yokohama, Japan

6. Department of Pediatrics, Kanazawa University Hospital, Kanazawa, Japan

7. Department of Pediatrics, Pediatric Allergy and Rheumatology Center, National Hospital Organization Shimoshizu National Hospital, Chiba, Japan

8. Novartis Pharma KK, Tokyo, Japan

9. Children’s Intractable Disease Rheumatism Center, Fuji Toranomon Orthopedics Hospital, Shizuoka, Japan

Funder

Novartis Pharma AG, Basel, Switzerland

Publisher

Oxford University Press (OUP)

Subject

Rheumatology

Reference50 articles.

1. Juvenile idiopathic arthritis

2. Systemic JIA as an Autoinflammatory Disease

3. Takei S, Yamashita S, Kato T. Nation-wide survey for patients with juvenile idiopathic arthritis in Japan. Annual Report on Children with Chronic Refractory Diseases from the Japanese Ministry of Health, Labor and Welfare 2008. p. 102–13.

4. Clinical analysis of 570 cases with juvenile rheumatoid arthritis: Results of a nationwide retrospective survey in Japan

5. Clinical practice guidance for juvenile idiopathic arthritis (JIA) 2018

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