Clinical predictors of inadequate response to conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) including methotrexate (MTX) in untreated rheumatoid arthritis patients: A single-center observational study.

Author:

Aramaki Toshiyuki1,Ueki Yukitaka1,Kojima Kanako1,Kurushima Shota1,Tsuji Yoshika1,Kawachi Natsumi1,Iwamoto Naoki2,Ichinose Kunihiro2,Terada Kaoru1,Eguchi Katsumi1,Kawakami Atsushi2

Affiliation:

1. Rheumatic Disease Center, Sasebo Chuo Hospital, Sasebo, Japan;

2. Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan

Publisher

Oxford University Press (OUP)

Subject

Rheumatology

Reference32 articles.

1. Smolen JS, Landewé R, Bijlsma J, Burmester G, Chatzidionysiou K, Dougados M, et al. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update. 2017;76:960–77.

2. 2015 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis

3. Disease activity early in the course of treatment predicts response to therapy after one year in rheumatoid arthritis patients

4. Old drugs, old problems: where do we stand in prediction of rheumatoid arthritis responsiveness to methotrexate and other synthetic DMARDs?

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