1. The First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health Japan, Kitakyushu, Japan;
2. GlaxoSmithKline, Philadelphia, PA, USA;
3. GlaxoSmithKline, Stevenage, UK;
4. Clinical Development, GlaxoSmithKline R&D, Uxbridge, UK;
5. Quantitative Clinical Development, PAREXEL, Durham, NC, USA