Replacing the 238th aspartic acid with an arginine impaired the oligomerization activity and inflammation-inducing property of pyolysin
Author:
Affiliation:
1. College of Veterinary Medicine, Northeast Agricultural University, Harbin, PR China
2. China Ministry of Agriculture Key Laboratory of Animal Pathogen Biology, Northeastern Science Inspection Station, Harbin, PR China
Funder
National Natural Science Foundation of China
University Nursing Program for Young Scholars with Creative Talents in Heilongjiang Province
“Academic Backbone” Project of Northeast Agricultural University
“Young Talents” Project of Northeast Agricultural University
Publisher
Informa UK Limited
Subject
Infectious Diseases,Microbiology (medical),Immunology,Microbiology,Parasitology
Link
https://www.tandfonline.com/doi/pdf/10.1080/21505594.2018.1491256
Reference35 articles.
1. Comparative chemotaxonomic and phylogenetic studies on the genus Arcanobacterium Collins et al. 1982 emend. Lehnen et al. 2006: proposal for Trueperella gen. nov. and emended description of the genus Arcanobacterium
2. Presence of Escherichia coli, Trueperella pyogenes, α-hemolytic streptococci, and coagulase-negative staphylococci and prevalence of subclinical endometritis
3. Arcanobacterium pyogenes: molecular pathogenesis of an animal opportunist
4. In vitro and in vivo expression of virulence genes in Trueperella pyogenes based on a mouse model
5. An Arcanobacterium ( Actinomyces ) pyogenes Mutant Deficient in Production of the Pore-Forming Cytolysin Pyolysin Has Reduced Virulence
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