Evaluation of the immunogenicity of auxotrophic Lactobacillus with CRISPR-Cas9D10A system-mediated chromosomal editing to express porcine rotavirus capsid protein VP4

Author:

Li Fengsai1,Mei Zhuyuan1,Ju Ning1,Sui Ling1,Fan Xiaolong1,Wang Zi2,Li Jiaxuan1,Jiang Yanping1,Cui Wen1,Shan Zhifu13,Zhou Han1,Wang Li13,Qiao Xinyuan13,Tang Lijie13,Wang Xiaona13,Li Yijing13

Affiliation:

1. College of Veterinary Medicine, Northeast Agricultural University, Harbin, Heilongjiang, China

2. Tongliao Institute of agriculture and animal husbandry, Tongliao City, China

3. Heilongjiang Key Laboratory for Animal Disease Control and Pharmaceutical Development, Harbin, Heilongjiang, China

Funder

the National Natural Science Foundation of China

Chinese Academy of Agricultural Sciences

Publisher

Informa UK Limited

Subject

Infectious Diseases,Microbiology (medical),Immunology,Microbiology,Parasitology

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