Intratumoural expression of IL-6/STAT3, IL-17 and FOXP3 immune cells in the immunosuppressive tumour microenvironment of colorectal cancer <i>Immune cells-positive for IL-6, STAT3, IL-17 and FOXP3 and colorectal cancer development</i>-Reference-Cited by-同舟云学术

Intratumoural expression of IL-6/STAT3, IL-17 and FOXP3 immune cells in the immunosuppressive tumour microenvironment of colorectal cancer Immune cells-positive for IL-6, STAT3, IL-17 and FOXP3 and colorectal cancer development

Published:2022-05-14 Issue:1 Volume:36 Page:327-338
ISSN:1310-2818
Container-title:Biotechnology & Biotechnological Equipment
language:en
Short-container-title:Biotechnology & Biotechnological Equipment

Author:

Gulubova Maya Vladova¹,Chonov Dimitur Chavdarov²³,Ivanova Koni Vancho¹,Hristova Mariyna Kostova⁴,Krasimirova-Ignatova Maria Magdalena⁴,Vlaykova Tatyana Ivanova⁵

Affiliation:

1. Department of Pathology, Trakia University, Medical Faculty, Stara Zagora, Bulgaria

2. Department of General and Operative Surgery, Trakia University, Medical Faculty, Stara Zagora Bulgaria

3. Ward of Operative Surgery, University Hospital “Prof. D-r Stoyan Kirkovich”, Stara Zagora, Bulgaria

4. Complex Oncology Centre, Stara Zagora, Bulgaria

5. Department of Chemistry and Biochemistry, Medical Faculty, Trakia University, Stara Zagora, Bulgaria

Funder

the National Science Fund, Bulgarian

Publisher

Informa UK Limited

Subject

Biotechnology

Link

https://www.tandfonline.com/doi/pdf/10.1080/13102818.2022.2072765

Reference81 articles.

1. Th17-type cytokines, IL-6 and TNF-α synergistically activate STAT3 and NF-kB to promote colorectal cancer cell growth

2. Leukocyte populations and IL-6 in the tumor microenvironment of an orthotopic colorectal cancer model

3. STAT3 activation

4. Loss of tumoral expression of soluble IL-6 receptor is associated with disease progression in colorectal cancer

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