Analgesic activity of some aroylhydrazone-based molecular hybrids with antiseizure activity: in vivo and in silico evaluations

Author:

Marchev Stanislav1,Andreeva-Gateva Pavlina12,Tzoneva Roumiana3,Surcheva Slavina1,Tzonev Alex1,Kamenova Kalina1,Angelova Violina T.4,Tchekalarova Jana5,Vlaskovska Mila1

Affiliation:

1. Department of Pharmacology and Toxicology, Faculty of Medicine, Medical University of Sofia, Sofia, Bulgaria;

2. Department of Internal Medicine, Pharmacology and Clinical Pharmacology, Faculty of Medicine, Sofia University “St. Kliment Ohridski”, Sofia, Bulgaria;

3. Department of Lipid-Protein Interactions, Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, Sofia, Bulgaria;

4. Department of Chemistry, Faculty of Pharmacy, Medical University of Sofia, Sofia, Bulgaria;

5. Department of Behaviour Neurobiology, Institute of Neurobiology, Bulgarian Academy of Sciences, Sofia, Bulgaria

Funder

National Science Fund of Bulgaria

Publisher

Informa UK Limited

Subject

Biotechnology

Reference63 articles.

1. National Institute for Health and Care Excellence [Internet]. Epilepsies: diagnosis and management. Clinical guideline [CG137]. 2018. Available from: https://www.nice.org.uk/guidance/cg137

2. Incidence of epilepsy: A systematic review and meta-analysis

3. Wilner AN. Comorbidities common even in newly diagnosed epilepsy. Medscape, C. 2016. Available from: https://www.medscape.com/viewarticle/872119

4. Comorbidities of epilepsy: current concepts and future perspectives

5. Comorbidity and Childhood Epilepsy: A Nationwide Registry Study

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