1. Department of Medicine, Kuopio University Hospital, Kuopio, Finland;
2. Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland;
3. Department of Medicine, Savonlinna Central Hospital, Savonlinna, Finland;
4. Department of Clinical Microbiology, University of Eastern Finland, Kuopio, Finland;
5. Department of Oncology, Kuopio University Hospital, Kuopio, Finland;
6. Department of Oncology, Oulu University Hospital, Oulu, Finland;
7. Department of Oncology, Central Hospital of Central Finland, Jyväskylä, Finland;
8. Department of Medicine, North Carelia Hospital District, Joensuu, Finland;
9. Finnish Medicines Agency, Kuopio, Finland;
10. Department of Oncology, Tampere University Hospital, Tampere, Finland;
11. Nordlab, Medical Research Center Oulu, Oulu University Hospital, Oulu, Finland;
12. Science Service Center, Kuopio University Hospital, Kuopio, Finland;
13. Laboratory Centre of Eastern Finland, Kuopio, Finland;
14. Department of Medicine, Kymenlaakso Central Hospital, Kotka, Finland