Objective quantification of BCL2 protein by multiplex immunofluorescence in routine biopsy samples of diffuse large B-cell lymphoma demonstrates associations with survival and BCL2 gene alterations-Reference-Cited by-同舟云学术

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Objective quantification of BCL2 protein by multiplex immunofluorescence in routine biopsy samples of diffuse large B-cell lymphoma demonstrates associations with survival and BCL2 gene alterations

Published:2020-01-16 Issue:6 Volume:61 Page:1334-1344
ISSN:1042-8194
Container-title:Leukemia & Lymphoma
language:en
Short-container-title:Leukemia & Lymphoma

Author:

Chen Lina¹,Tyryshkin Kathrin¹,Moore Alison¹,Scott David W.²,Steidl Christian²,Li Yi¹,Shepherd Lois E.¹³,Rauh Michael¹,Deng Lan¹,Good David¹,Virk Shakeel¹,Chen Bingshu E.³,Crocker Susan¹,Baetz Tara⁴,LeBrun David P.¹

Affiliation:

1. Department of Pathology and Molecular Medicine, Queen’s University, Kingston, Canada;

2. BC Cancer Agency Centre for Lymphoid Cancer, Vancouver, Canada;

3. Canadian Cancer Trials Group, Kingston, Canada;

4. Department of Medical Oncology, Queen’s University, Kingston, Canada

Publisher

Informa UK Limited

Subject

Cancer Research,Oncology,Hematology

Link

https://www.tandfonline.com/doi/pdf/10.1080/10428194.2020.1713318

Reference35 articles.

1. Thirty years of BCL-2: translating cell death discoveries into novel cancer therapies

2. Targeting BCL2 with Venetoclax in Relapsed Chronic Lymphocytic Leukemia

3. BCL-2 as therapeutic target for hematological malignancies

4. ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

5. Targeting of BCL2 Family Proteins with ABT-199 and Homoharringtonine Reveals BCL2- and MCL1-Dependent Subgroups of Diffuse Large B-Cell Lymphoma

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1. Expression of TCF3 target genes defines a subclass of diffuse large B-cell lymphoma characterized by up-regulation of MYC target genes and poor clinical outcome following R-CHOP therapy;Leukemia & Lymphoma;2022-11-06

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