Adapted risk stratification and intensive chemotherapy abrogate the poor prognosis of pediatric B acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21 (iAMP21): a National cohort analysis-Reference-Cited by-同舟云学术

Adapted risk stratification and intensive chemotherapy abrogate the poor prognosis of pediatric B acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21 (iAMP21): a National cohort analysis

Published:2023-11 Issue:2 Volume:65 Page:279-282
ISSN:1042-8194
Container-title:Leukemia & Lymphoma
language:en
Short-container-title:Leukemia & Lymphoma

Author:

Trinquand Amélie¹,Betts David R.²,Harte Shauna¹,Sills Aoife¹,Rooney Sean³,Barrett Neil¹,Storey Lorna¹,Malone Andrea¹,O’Marcaigh Aengus¹,Smith Owen P.¹

Affiliation:

1. National Children’s Cancer Service, Children’s Health Ireland at Crumlin, Dublin, Ireland

2. Department of Clinical Genetics, Children’s Health Ireland at Crumlin, Dublin, Ireland

3. Haematology Laboratory, Children’s Health Ireland at Crumlin, Dublin, Ireland

Publisher

Informa UK Limited

Subject

Cancer Research,Oncology,Hematology

Link

https://www.tandfonline.com/doi/pdf/10.1080/10428194.2023.2276061

Reference15 articles.

1. Amplification of AML1 on a duplicated chromosome 21 in acute lymphoblastic leukemia: a study of 20 cases

2. Amplification of band q22 of chromosome 21, including AML1, in older children with acute lymphoblastic leukemia: an emerging molecular cytogenetic subgroup

3. Prognosis of children with acute lymphoblastic leukemia (ALL) and intrachromosomal amplification of chromosome 21 (iAMP21)

4. Intrachromosomal Amplification of Chromosome 21 Is Associated With Inferior Outcomes in Children With Acute Lymphoblastic Leukemia Treated in Contemporary Standard-Risk Children's Oncology Group Studies: A Report From the Children's Oncology Group

5. Risk-Directed Treatment Intensification Significantly Reduces the Risk of Relapse Among Children and Adolescents With Acute Lymphoblastic Leukemia and Intrachromosomal Amplification of Chromosome 21: A Comparison of the MRC ALL97/99 and UKALL2003 Trials