Acute myeloid leukemias with JAK2/STAT mutations are associated with PD-L1 upregulation-Reference-Cited by-同舟云学术

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Acute myeloid leukemias with JAK2/STAT mutations are associated with PD-L1 upregulation

Published:2023-07-10 Issue:10 Volume:64 Page:1662-1672
ISSN:1042-8194
Container-title:Leukemia & Lymphoma
language:en
Short-container-title:Leukemia & Lymphoma

Author:

Chai Jiani¹,Choudhuri Jui¹,Wang Qing¹,Fang Yanan¹^ORCID,Shi Yang¹,Kamel Josette²,Shah Nishi²^ORCID,Sica R. Alejandro²,Kornblum Noah²,Konopleva Marina²,Mantzaris Ioannis²,Shastri Aditi²,Gritsman Kira²,Verma Amit²,Goldfinger Mendel²,Goel Swati²,Wang Yanhua¹,Tian Xuejun¹³^ORCID

Affiliation:

1. Department of Pathology, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY, USA

2. Department of Hematology-Oncology, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY, USA

3. Department of Pathology, Thomas Jefferson University Hospital, Philadelphia, PA, USA

Publisher

Informa UK Limited

Subject

Cancer Research,Oncology,Hematology

Link

https://www.tandfonline.com/doi/pdf/10.1080/10428194.2023.2232494

Reference26 articles.

1. PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy: Mechanisms, response biomarkers, and combinations

Research Status and Outlook of PD-1/PD-L1 Inhibitors for Cancer Therapy

3. Immune checkpoint inhibitors of PD-L1 as cancer therapeutics

4. Targeting PD-1/PD-L1 pathway in myelodysplastic syndromes and acute myeloid leukemia

5. In acute myeloid leukemia, B7-H1 (PD-L1) protection of blasts from cytotoxic T cells is induced by TLR ligands and interferon-gamma and can be reversed using MEK inhibitors

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