Double minute chromosomes in acute myeloid leukemia and myelodysplastic syndromes are associated with complex karyotype, monosomal karyotype, TP53 deletion, and TP53 mutations
Author:
Affiliation:
1. Department of Hematology, Chinese PLA General Hospital, Beijing, China
2. Department of Hematology-Oncology, International Cancer Center, Shenzhen University General Hospital, Shenzhen University Health Science Center, Shenzhen, China
Publisher
Informa UK Limited
Subject
Cancer Research,Oncology,Hematology
Link
https://www.tandfonline.com/doi/pdf/10.1080/10428194.2021.1919663
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1. Have double minutes functioning centromeres?
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4. Apparent lack of telomere sequences on double minute chromosomes
5. Presence of telomeric sequences on deleted chromosomes and their absence on double minutes in cell line HL-60
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