Response to Letter to the Editor from Drs. van Kesteren, Pronk, Heusinkveld, Luijten and Hakkert concerning Yamada et al. (2021): Critical evaluation of the human relevance of the mode of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR). Crit. Rev. Toxicol. Vol. 51: 373-394.-Reference-Cited by-同舟云学术

Response to Letter to the Editor from Drs. van Kesteren, Pronk, Heusinkveld, Luijten and Hakkert concerning Yamada et al. (2021): Critical evaluation of the human relevance of the mode of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR). Crit. Rev. Toxicol. Vol. 51: 373-394.

Published:2022-05-28 Issue:5 Volume:52 Page:399-402
ISSN:1040-8444
Container-title:Critical Reviews in Toxicology
language:en
Short-container-title:Critical Reviews in Toxicology

Author:

Yamada Tomoya¹^ORCID,Cohen Samuel M.²^ORCID,Lake Brian G³

Affiliation:

1. Sumitomo Chemical Company Ltd, Environmental Health Science Laboratory, Osaka, Japan

2. Department of Pathology and Microbiology, Havlik-Wall Professor of Oncology, University of Nebraska Medical Center, Omaha, NE, USA

3. School of Biosciences and Medicine Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, UK

Funder

Sumitomo Chemical Company, Ltd.

Publisher

Informa UK Limited

Subject

Toxicology

Link

https://www.tandfonline.com/doi/pdf/10.1080/10408444.2022.2101915

Reference27 articles.

1. IPCS Framework for Analyzing the Relevance of a Cancer Mode of Action for Humans

2. Mode of action framework analysis for receptor-mediated toxicity: The peroxisome proliferator-activated receptor alpha (PPARα) as a case study

3. The PPARα-dependent rodent liver tumor response is not relevant to humans: addressing misconceptions

4. ECHA. 2017. Guidance on the application of the CLP criteria, Guidance to regulation (EC) No 1272/2008 on classification, labelling and packaging (CLP) of substances and mixtures, version 5.0. (accessed 6/22/2022).

5. Chimeric Mouse With Humanized Liver Is an Appropriate Animal Model to Investigate Mode of Action for Porphyria-Mediated Hepatocytotoxicity