Transgenic mice recapitulate the phenotypic heterogeneity of genetic prion diseases without developing prion infectivity: Role of intracellular PrP retention in neurotoxicity
Author:
Affiliation:
1. Laboratory of Prion Neurobiology, Department of Neuroscience, IRCCS – “Mario Negri” Institute for Pharmacological Research, Milan, Italy;
2. Department of Health Sciences, University of Milan Medical School, Milan, Italy
Publisher
Informa UK Limited
Subject
Infectious Diseases,Cell Biology,Cellular and Molecular Neuroscience,Biochemistry
Link
https://www.tandfonline.com/doi/pdf/10.1080/19336896.2016.1139276
Reference36 articles.
1. The genetics of prion diseases
2. A Novel Prion Disease Associated with Diarrhea and Autonomic Neuropathy
3. Nobel Lecture: Prions
4. Evidence for the Conformation of the Pathologic Isoform of the Prion Protein Enciphering and Propagating Prion Diversity
5. Inherited Prion Diseases and Transmission to Rodents
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