Zero-link polymerized hemoglobin (OxyVita®Hb) stabilizes the heme environment: potential for lowering vascular oxidative stress
Author:
Affiliation:
1. OXYVITA Inc., New Windsor, NY, USA;
2. Department of Chemistry, State University of New York, New Paltz, NY, USA;
3. Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA
Publisher
Informa UK Limited
Subject
Pharmaceutical Science,Biomedical Engineering,General Medicine,Medicine (miscellaneous),Biotechnology
Link
https://www.tandfonline.com/doi/pdf/10.1080/21691401.2016.1263639
Reference12 articles.
1. Hemoglobin and free radicals: implications for the development of a safe blood substitute
2. Production and characteristics of an infusible oxygen-carrying fluid based on hemoglobin intramolecularly cross-linked with sebacic acid
3. Hemoglobin Autooxidation/Oxidation Mechanisms and Methemoglobin Prevention or Reduction Processes in the Bloodstream Literature review and outline of autooxidation reaction
4. Hierarchical Structures of Natural Acellular Polymeric Hemoglobins: Model for Design of a Therapeutic Hemoglobin-Based-Oxygen-Carrier (HBOC)
5. Structural and Redox Behavior of OxyVita™, a Zero-linked Polymeric Hemoglobin: Comparison with Natural Acellular Polymeric Hemoglobins
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