Polyarginine and PEG-AEYLR comodified nanostructured lipid carrier: 10mol% uncleavable PEG-AEYLR showed no shielding effect to polyarginine in vitro while maintaining good tumor targeting in vivo
Author:
Affiliation:
1. School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, China;
2. School of Pharmacy, Qiqihar Medical University, Qiqihar, China
Funder
National Natural Science foundation of China
Department of Education, Heilongjiang Province
Publisher
Informa UK Limited
Subject
Pharmaceutical Science,Biomedical Engineering,General Medicine,Medicine (miscellaneous),Biotechnology
Link
https://www.tandfonline.com/doi/pdf/10.1080/21691401.2017.1307211
Reference28 articles.
1. Stealth nanoparticles: High density but sheddable PEG is a key for tumor targeting
2. The effect of PEG-5K grafting level and particle size on tumor accumulation and cellular uptake
3. Study of PEGylated Lipid Layers as a Model for PEGylated Liposome Surfaces: Molecular Dynamics Simulation and Langmuir Monolayer Studies
4. Multifunctional PEGylated 2C5-immunoliposomes containing pH-sensitive bonds and TAT peptide for enhanced tumor cell internalization and cytotoxicity
5. A Comparison between the cytotoxic effects of pure curcumin and curcumin-loaded PLGA-PEG nanoparticles on the MCF-7 human breast cancer cell line
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