Applications of Magnetic Resonance Microscopy

Author:

Maronpot Robert R.1,Sills Robert C.2,Johnson G. Allan3

Affiliation:

1. National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA, Maronpot@niehs.nih.gov

2. National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA

3. Duke Center for In Vivo Microscopy, Duke University Medical Center, Durham, North Carolina 27710, USA

Abstract

Magnetic resonance imaging (MRI) has enjoyed enormous clinical success since the first demonstration of the method more than 30 years ago. An increasing number of pharmaceutical manufacturers seeking new biomarkers for assessing drug efficacy and toxicity are turning to MRI. A specific application of MRI promises to revolutionize pathology for the basic scientist in the same way MRI has forever altered the standard of care in the clinical domain. More specifically, this application is the use of magnetic resonance microscopy (MRM) in conjunction with new staining methodologies that now make MRM routinely available to the widest range of investigators.

Publisher

SAGE Publications

Subject

Cell Biology,Toxicology,Molecular Biology,Pathology and Forensic Medicine

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