Recommended Approaches for the Evaluation of Testicular and Epididymal Toxicity

Author:

Lanning Lynda L.1,Creasy Dianne M.2,Chapin Robert E.3,Mann Peter C.4,Barlow Norman J.5,Regan Karen S.6,Goodman Dawn G.7

Affiliation:

1. BioReliance Corporation, Rockville, Maryland, 20850

2. Huntingdon Life Sciences, East Millstone, New Jersey 08875

3. Pfizer Inc, Groton, Connecticut 06340

4. Experimental Pathology Laboratory NorthEast, Galena, Maryland 21635

5. Chemical Industry Institute of Toxicology, Research Triangle Park, North Carolina 27709

6. Regan Path/Tox Services, Ashland, Ohio 44805

7. Covance Laboratories Inc, Vienna, Virginia 22182

Publisher

SAGE Publications

Subject

Cell Biology,Toxicology,Molecular Biology,Pathology and Forensic Medicine

Reference37 articles.

1. Optimal replication for histometric analyses of testicular function in rats or rabbits*1

2. Leuprolide, a Gonadotropin-Releasing Hormone Agonist, Reestablishes Spermatogenesis After 2,5-Hexanedione-Induced Irreversible Testicular Injury in the Rat, Resulting in Normalized Stem Cell Factor Expression*

3. Boorman GA, Chapin RE, Mitsumori K. (1990). Testis and Epididymis. In: Pathology of the Fischer Rat: Reference and Atlas, Boorman GA, Eustis SL, Elwell MR, Montgomery CA, MacKenzie WF (eds). Academic Press, San Diego, pp 405—418.

4. Chapin RE, Conner MW (1999). Testicular histology and sperm parameters. In: An Evaluation and Interpretation of Reproductive Endpoints for Human Health Risk Assessment, Daston G, Kimmel C (eds). ILSI Press, Washington, DC, pp 28—41.

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