Pharmacokinetics of ingenol mebutate gel under maximum use conditions in large treatment areas
Author:
Affiliation:
1. Academic Dermatology Associates, Albuquerque, NM, USA;
2. DermResearch, Inc., Austin, TX, USA;
3. Burke Pharmaceutical Research, Hot Springs, AR, USA;
4. LEO Pharma, Ballerup, Denmark
Funder
LEO Pharma Research Foundation
LEO Pharma
Publisher
Informa UK Limited
Subject
Dermatology
Link
https://www.tandfonline.com/doi/pdf/10.1080/09546634.2017.1329506
Reference18 articles.
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2. The natural history of actinic keratosis: a systematic review
3. Pathology and pathobiology of actinic (solar) keratosis - an update
4. New developments in the treatment of actinic keratosis: focus on ingenol mebutate gel
5. Werner RN, Stockfleth E, Connolly SM, et al. Evidence and consensus based (S3) guidelines for the treatment of actinic keratosis. 2015. Available from: http://www.euroderm.org/edf/index.php/edf-guidelines/category/5-guidelines-miscellaneous?download=23:guideline-management-of-actinic-keratoses-update-2015. Accessed August 28, 2015.
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2. Targeting Cutaneous T-Cell Lymphoma Cells by Ingenol Mebutate (PEP005) Correlates with PKCδ Activation, ROS Induction as Well as Downregulation of XIAP and c-FLIP;Cells;2021-04-23
3. Ingenol mebutate 0·015% gel is safe for short‐term treatment of actinic keratoses on the face in solid organ transplant recipients;British Journal of Dermatology;2020-05-26
4. Efficacy and safety of ingenol mebutate gel in field treatment of actinic keratosis on full face, balding scalp, or approximately 250 cm2 on the chest: A phase 3 randomized controlled trial;Journal of the American Academy of Dermatology;2020-03
5. Ingenol mebutate treatment in actinic keratosis – clinical effectiveness and potential side effects;Advances in Dermatology and Allergology;2019
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