Embedding a COVID-19 group sequential clinical trial within an ongoing trial: lessons from an unusual experience-Reference-Cited by-同舟云学术

Embedding a COVID-19 group sequential clinical trial within an ongoing trial: lessons from an unusual experience

Published:2020-08-19 Issue:4 Volume:12 Page:478-482
ISSN:1946-6315
Container-title:Statistics in Biopharmaceutical Research
language:en
Short-container-title:Statistics in Biopharmaceutical Research

Author:

Dequin Pierre-François¹,Gouge Amélie Le²,Tavernier Elsa²,Giraudeau Bruno²³,Zohar Sarah⁴

Affiliation:

1. Service de Médecine Intensive-Réanimation, CHRU de Tours, France; INSERM U1100, Centre d'Etude des Pathologies Respiratoires, Université de Tours, Tours, France.;

2. INSERM CIC1415, CHRU de Tours, Tours, France.;

3. Université de Tours, Université de Nantes, INSERM, SPHERE U1246, Tours, France;

4. INSERM, Centre de Recherche des Cordeliers, Sorbonne Université, Université de Paris, Paris, France

Publisher

Informa UK Limited

Subject

Pharmaceutical Science,Statistics and Probability

Link

https://www.tandfonline.com/doi/pdf/10.1080/19466315.2020.1800509

Reference15 articles.

1. Guidance on the Management of Clinical Trials during the COVID-19 (Coronavirus) pandemic [Internet]. [cited 2020 May 8]. Available from: https://ec.europa.eu/health/sites/health/files/files/eudralex/vol-10/guidanceclinicaltrials_covid19_en.pdf

2. Against pandemic research exceptionalism

3. Clinical evidence does not support corticosteroid treatment for 2019-nCoV lung injury

4. Group Sequential Clinical Trials with Triangular Continuation Regions

5. Group sequential methods in the design and analysis of clinical trials

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