Shrinkage Estimation for Dose–Response Modeling in Phase II Trials With Multiple Schedules
Author:
Affiliation:
1. Department of Medical Statistics, University Medical Center Göttingen, Göttingen, Germany;
2. Galapagos NV, Mechelen, Belgium
Publisher
Informa UK Limited
Subject
Pharmaceutical Science,Statistics and Probability
Link
https://www.tandfonline.com/doi/pdf/10.1080/19466315.2020.1850519
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2. =EFFICACY AND SAFETY OF BOCOCIZUMAB (RN316/PF-04950615), A MONOCLONAL ANTIBODY AGAINST PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 IN STATIN-TREATED HYPERCHOLESTEROLEMIC SUBJECTS: RESULTS FROM A RANDOMIZED, PLACEBO-CONTROLLED, DOSE-RANGING STUDY (NCT: 01592240)
3. Hamiltonian Monte Carlo for Hierarchical Models
4. Functional Uniform Priors for Nonlinear Modeling
5. Practical considerations for using functional uniform prior distributions for dose-response estimation in clinical trials
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