A Versatile Adaptive Dose-Finding Design Based on Multiple Endpoints-Reference-Cited by-同舟云学术

A Versatile Adaptive Dose-Finding Design Based on Multiple Endpoints

Published:2017-07-03 Issue:3 Volume:9 Page:302-313
ISSN:1946-6315
Container-title:Statistics in Biopharmaceutical Research
language:en
Short-container-title:Statistics in Biopharmaceutical Research

Author:

Baayen Corine¹²³,Hougaard Philip²,Pipper C. B.³

Affiliation:

1. Capionis, Bordeaux, France

2. Biometrics Division, H. Lundbeck A/S, Valby, Denmark

3. Department of Biostatistics, University of Copenhagen, Copenhagen, Denmark

Publisher

Informa UK Limited

Subject

Pharmaceutical Science,Statistics and Probability

Link

https://www.tandfonline.com/doi/pdf/10.1080/19466315.2017.1341333

Reference29 articles.

1. A Bayesian Approach to Jointly Modeling Toxicity and Biomarker Expression in a Phase I/II Dose-Finding Trial

2. Bornkamp, B., Pinheiro, J., and Bretz, F. (2014), “Dosefinding: Planning and c, 2014,” R Package Version 0.9-5, available at http://CRAN.R-project.org/package=DoseFinding.

3. The bivariate continual reassessment method

4. Designing Experiments with Respect to 'Standardized' Optimality Criteria

5. Innovation in the pharmaceutical industry: New estimates of R&D costs

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