A Bayesian Adaptive Umbrella Trial Design with Robust Information Borrowing for Screening Multiple Combination Therapies
Author:
Affiliation:
1. Center for Design and Analysis, Amgen Inc., Thousand Oaks, CA
2. Department of Biostatistics, University of California, Los Angeles, CA
Publisher
Informa UK Limited
Subject
Pharmaceutical Science,Statistics and Probability
Link
https://www.tandfonline.com/doi/pdf/10.1080/19466315.2023.2215735
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4. An efficient basket trial design
5. MORPHEUS: A phase Ib/II study platform evaluating the safety and clinical efficacy of cancer immunotherapy (CIT)–based combinations in gastrointestinal (GI) cancers.
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