Efficacy and epigenetic interactions of novel DNA hypomethylating agent guadecitabine (SGI-110) in preclinical models of hepatocellular carcinoma-Reference-Cited by-同舟云学术

Efficacy and epigenetic interactions of novel DNA hypomethylating agent guadecitabine (SGI-110) in preclinical models of hepatocellular carcinoma

Published:2016-09-20 Issue:10 Volume:11 Page:709-720
ISSN:1559-2294
Container-title:Epigenetics
language:en
Short-container-title:Epigenetics

Author:

Jueliger Simone¹,Lyons John¹,Cannito Sara²³,Pata Illar⁴,Pata Pille⁴,Shkolnaya Marianna⁴,Lo Re Oriana⁵,Peyrou Marion⁶,Villarroya Francesc⁶,Pazienza Valerio²,Rappa Francesca⁷⁸,Cappello Francesco⁷⁸,Azab Mohammad⁹,Taverna Pietro⁹,Vinciguerra Manlio²³⁵⁸

Affiliation:

1. Astex Pharmaceuticals, Cambridge, UK

2. Gastroenterology Unit, IRCCS “Casa Sollievo della Sofferenza” Hospital, San Giovanni Rotondo, Italy

3. Institute for Liver and Digestive Health, University College London (UCL), Royal Free Hospital, London, UK

4. Department of Gene Technology, Tallinn University of Technology (TTU), IVEX Lab, Tallinn, Estonia

5. Center for Translational Medicine (CTM), International Clinical Research Center (ICRC), St. Anne's University Hospital, Brno, Czech Republic

6. Departament de Bioquímica i Biologia Molecular, Institute of Biomedicine (IBUB), University of Barcelona, Barcelona, Spain

7. Department of Experimental Biomedicine and Clinical Neurosciences, Section of Human Anatomy, University of Palermo, Palermo, Italy

8. Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy

9. Astex Pharmaceuticals, Pleasanton, CA, USA

Publisher

Informa UK Limited

Subject

Cancer Research,Molecular Biology

Link

https://tandfonline.com/doi/pdf/10.1080/15592294.2016.1214781

Reference45 articles.

1. HCC—subtypes, stratification and sorafenib

2. Liver diseases and aging: friends or foes?

3. DNA Hypomethylation and Histone Variant macroH2A1 Synergistically Attenuate Chemotherapy-Induced Senescence to Promote Hepatocellular Carcinoma Progression

4. Genome-Wide Methylation Analysis and Epigenetic Unmasking Identify Tumor Suppressor Genes in Hepatocellular Carcinoma

5. DNA methylation-based prognosis and epidrivers in hepatocellular carcinoma

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