Loss of KMT2C reprograms the epigenomic landscape in hPSCs resulting in NODAL overexpression and a failure of hemogenic endothelium specification-Reference-Cited by-同舟云学术

Loss of KMT2C reprograms the epigenomic landscape in hPSCs resulting in NODAL overexpression and a failure of hemogenic endothelium specification

Published:2021-07-24 Issue: Volume: Page:1-19
ISSN:1559-2294
Container-title:Epigenetics
language:en
Short-container-title:Epigenetics

Author:

Maurya Shailendra¹,Yang Wei²,Tamai Minori¹,Zhang Qiang³,Erdmann-Gilmore Petra³,Bystry Amelia¹,Martins Rodrigues Fernanda³,Valentine Mark C.¹,Wong Wing H¹,Townsend Reid³,Druley Todd E.¹^ORCID

Affiliation:

1. Department of Pediatrics, Division of Pediatric Hematology and Oncology, Washington University in St Louis School of Medicine, St. Louis, Missouri, United States

2. McDonnell Genome Institute, Genome Technology Access Center, Washington University in St Louis School of Medicine, St. Louis, Missouri, United States

3. Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri, USA

Funder

National Cancer Institute

National Institute of General Medical Sciences

Eli Seth Matthews Leukemia Foundation

Kellsie’s Hope Foundation

Institute for Clinical and Translational Research, Washington University School of Medicine

Publisher

Informa UK Limited

Subject

Cancer Research,Molecular Biology

Link