Reactivation of hyperglycemia-induced hypocretin (HCRT) gene silencing by N-acetyl-d-mannosamine in the orexin neurons derived from human iPS cells

Author:

Hayakawa Koji1ORCID,Sakamoto Yasuharu2,Kanie Osamu34ORCID,Ohtake Atsuko3,Daikoku Shusaku3,Ito Yukishige23ORCID,Shiota Kunio15

Affiliation:

1. Laboratory of Cellular Biochemistry, Department of Animal Resource Sciences/Veterinary Medical Sciences, The University of Tokyo, Tokyo, Japan

2. Synthetic Cellular Chemistry Laboratory, RIKEN, 2-1 Hirosawa, Wako, Saitama, Japan

3. Japan Science and Technology Agency ERATO Glycotrilogy Project, 2-1 Hirosawa, Wako, Saitama, Japan

4. Present address: Institute of Advanced Biosciences, Tokai University, 4-1-1 Kitakaname, Hiratsuka, Kanagawa, Japan

5. Waseda Research Institute for Science and Engineering, Waseda University, Tokyo, Japan

Funder

Grant-in-Aid for Scientific Research A from the Ministry of Education, Culture, Sports, Science and Technology, Japan

Publisher

Informa UK Limited

Subject

Cancer Research,Molecular Biology

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