Cardiac adenovirus-associated viral Presenilin 1 gene delivery protects the left ventricular function of the heart via regulating RyR2 function in post-ischaemic heart failure
Author:
Affiliation:
1. Department of Biophysics, College of Basic Medical Sciences, Second Military Medical University, Shanghai, China;
2. School of Pharmacy, Second Military Medical University, Shanghai, China;
3. Pharchoice Therapeutics Inc, Shanghai, China
Funder
National Natural Science Foundation of China
Second Military Medical University
China Postdoctoral Science Foundation
Publisher
Informa UK Limited
Subject
Pharmaceutical Science
Link
https://www.tandfonline.com/doi/pdf/10.1080/1061186X.2018.1450412
Reference36 articles.
1. Alterations of calcium-regulatory proteins in heart failure
2. Fixing ryanodine receptor Ca2+ leak – a novel therapeutic strategy for contractile failure in heart and skeletal muscle
3. Phosphodiesterase 4D Deficiency in the Ryanodine-Receptor Complex Promotes Heart Failure and Arrhythmias
4. Stabilization of cardiac ryanodine receptor prevents intracellular calcium leak and arrhythmias
5. Abnormal intracellular calcium handling in myocardium from patients with end-stage heart failure.
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