Development of freeze-drying cycle via design space approach: a case study on vaccines
Author:
Affiliation:
1. GSK Vaccines, Rixensart, Belgium
Funder
GlaxoSmithKline Biologicals SA
Publisher
Informa UK Limited
Subject
Pharmaceutical Science,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/10837450.2020.1806298
Reference50 articles.
1. Prediction of Ice Crystal Size Distribution after Freezing of Pharmaceutical Solutions
2. Considerations on Protein Stability During Freezing and Its Impact on the Freeze-Drying Cycle: A Design Space Approach
3. Application of the Quality by Design Approach to the Freezing Step of Freeze-Drying: Building the Design Space
4. Measuring and predicting pore size distribution of freeze-dried solutions
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